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| | |
PPLpre
|
|---|
| |
Haplotypes
|
Coefficient
|
SE
|
CI
|
z-score
|
p value
|
|---|
|
1
|
ACGGAC
|
13.245
|
6.576
|
(0.357, 26.134)
|
2.014
|
0.044
|
|
2
|
GCGGAC
|
-0.23
|
4.252
|
(-8.563, 8.103)
|
-0.05
|
0.957
|
|
3
|
GTAAAC
|
-7.275
|
2.34
|
(-11.860, -2.689)
|
-3.11
|
0.002
|
| | |
Analgesic effect (PPLpost-PPLpre)
|
| | |
Coefficient
|
SE
|
CI
|
z-score
|
p
value
|
|
1
|
ACGGAC
|
19.452
|
9.34
|
(1.146, 37.759)
|
2.083
|
0.037
|
|
2
|
GCGGAC
|
-2.966
|
6.87
|
(-16.431, 10.499)
|
-0.43
|
0.666
|
|
3
|
GTAAAC
|
-14.97
|
4.585
|
(-23.957, -5.983)
|
-3.27
|
0.001
|
| | |
VAS pain score at 24 h
|
| | |
Coefficient
|
SE
|
CI
|
z-score
|
p
value
|
|
1
|
ACGGAC
|
7.878
|
4.067
|
(-0.094, 15.849)
|
1.937
|
0.053
|
|
2
|
GCGGAC
|
-10.799
|
3.523
|
(-17.705, -3.894)
|
-3.07
|
0.002
|
|
3
|
GTAAAC
|
7.434
|
8.88
|
(-9.971, 24.839)
|
0.837
|
0.402
|
- Haplotype-based associations were tested using linear regression analyses with a recessive model.
